Parkinsons disease is a degenerative condition of a specific group of brain cells (substantia nigra) with an imbalance of two neurotransmitters: low dopamine and high acetylcholine. This imbalanced combination of brain messengers account for the muscle rigidity and tremors seen with this disease.
It usually has a gradual onset beginning with a slight tremor. Slowly this increases and spreads to different muscles throughout the body. Muscle cramps and constipation are common with this disease. Eventually it can progress to the point where everyday activities become very difficult or not possible. Despite the physical inabilities one endures, Parkinsons does not affect cognitive abilities in most cases.
There is no known exact cause fro the deterioration of the brain cells. The following are believed to be influential factors with Parkinsons disease:
Excess carbon monoxide
Heavy metal toxicity i.e. aluminum, mercury
of brain cells due to an increased production of free radicals or a depleted
reserve of anti-oxidants to eliminate them
Other factors to be considered when addressing Parkinsons disease: